Clinical Pharmacy and Patient Care Flashcards
6 cards from real MPharm Master of Pharmacy practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Clinical Pharmacy and Patient Care flashcards as text
Which antidiabetic drug class carries the highest risk of hypoglycemia when used as monotherapy?
Answer: Sulfonylureas
Sulfonylureas stimulate insulin secretion independent of glucose levels, making hypoglycemia a primary adverse effect.
A clinical pharmacist identifies a patient on lisinopril who develops a persistent dry cough. What is the recommended intervention?
Answer: Switch to an ARB such as losartan
ACE inhibitor-induced cough is a class effect due to bradykinin accumulation; switching to an ARB eliminates this side effect.
Which renal function metric is most important for dose adjustment recommendations in clinical pharmacy?
Answer: Estimated GFR (eGFR)
eGFR quantifies kidney filtration capacity and is the standard basis for renal dose adjustments of renally cleared drugs.
A patient with atrial fibrillation and CrCl of 40 mL/min needs anticoagulation. Which DOAC requires the most significant dose reduction?
Answer: Dabigatran
Dabigatran is approximately 80% renally eliminated and requires significant dose reduction or avoidance at CrCl < 50 mL/min.
What is the purpose of a pharmacist-conducted medication reconciliation at hospital admission?
Answer: Create a complete and accurate list of current medications to prevent discrepancies
Medication reconciliation compares the patient's home medication list to admission orders to prevent omissions, duplications, and errors.
Which tool is used by clinical pharmacists to assess the appropriateness of medications in elderly patients?
Answer: Beers Criteria
The AGS Beers Criteria lists medications that are potentially inappropriate for use in older adults due to increased risks of adverse effects.