MLS Blood Banking & Transfusion Medicine 3

Question 1

What is the correct storage temperature for packed red blood cells (pRBCs)?

Accepted Answer

1–6°C

Answer

Packed red blood cells must be stored at 1–6°C in a monitored blood bank refrigerator to slow cell metabolism and prevent bacterial proliferation while avoiding freezing.

Question 2

Fresh Frozen Plasma (FFP) is most appropriately indicated for:

Accepted Answer

Multiple coagulation factor deficiencies (e.g., DIC, liver disease, warfarin reversal)

Answer

FFP contains all coagulation factors in plasma and is indicated for deficiencies of multiple factors as seen in DIC, liver failure, or to reverse warfarin anticoagulation rapidly.

Question 3

Cryoprecipitate is the blood product of choice for providing which coagulation factors?

Accepted Answer

Factor VIII, Factor XIII, fibrinogen, and von Willebrand factor

Answer

Cryoprecipitate is prepared from the cold-insoluble portion of FFP and is concentrated in Factor VIII, Factor XIII, fibrinogen, and von Willebrand factor, making it useful in hemophilia A, vWD, and hypofibrinogenemia.

Question 4

Gamma irradiation of blood products is performed primarily to prevent:

Accepted Answer

Transfusion-associated graft-versus-host disease (TA-GvHD)

Answer

Irradiation inactivates viable donor T-lymphocytes that could engraft in immunocompromised recipients and attack host tissues, causing the frequently fatal TA-GvHD.

Question 5

What is the maximum allowable storage period for packed red blood cells in CPDA-1 preservative solution?

Accepted Answer

35 days

Answer

CPDA-1 (citrate-phosphate-dextrose-adenine) anticoagulant-preservative solution maintains red cell adenine and glucose metabolism for up to 35 days at 1–6°C.

(MLS) Medical Laboratory Scientist Practice Test

(MLS) Medical Laboratory Scientist Practice Test

MLS Blood Banking & Transfusion Medicine 3