Medical Technologist Test Clinical Chemistry 3

Question 1

Serum creatinine is primarily used to assess the function of which organ?

Accepted Answer

Kidney

Answer

Creatinine is filtered by the glomerulus and serves as a reliable endogenous marker of glomerular filtration rate (GFR).

Question 2

Which condition causes a true decrease in serum albumin?

Accepted Answer

Nephrotic syndrome

Answer

Nephrotic syndrome causes massive urinary protein loss, leading to hypoalbuminemia and oncotic pressure changes.

Question 3

A patient with hypothyroidism would most likely show which thyroid function test pattern?

Accepted Answer

High TSH with low free T4

Answer

Primary hypothyroidism shows elevated TSH (pituitary compensation) and decreased free T4 due to reduced thyroid output.

Question 4

Phenylketonuria (PKU) is caused by a deficiency of which enzyme?

Accepted Answer

Phenylalanine hydroxylase

Answer

PKU results from deficient phenylalanine hydroxylase, causing phenylalanine accumulation and intellectual disability if untreated.

Question 5

Which specimen tube should be used for serum chemistry testing?

Accepted Answer

Red or gold (SST)

Answer

Red or gold SST (serum separator) tubes allow blood to clot; serum is separated by centrifugation for most chemistry panels.

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