ISAC Study Guide 2026
Everything you need to pass the ISAC exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 ISAC Exam Format at a Glance
📚 ISAC Topics to Study (63)
✍️ Sample ISAC Questions & Answers
1. What should a ISAC professional do when they encounter a situation beyond their competence?
Recognizing the limits of ones competence and making appropriate referrals is a fundamental professional responsibility.
2. What is the role of a Laboratory Information System (LIS) in flow cytometry documentation?
An LIS integrates specimen ordering, result entry, and audit trails into a centralized system that supports traceability and regulatory compliance.
3. What is the minimum information that must be recorded when a flow cytometry reagent (antibody conjugate) is opened for the first time?
Opening records must capture date opened, lot number, expiration date, and operator initials to ensure reagent traceability and compliance with expiration policies.
4. What is the purpose of an account lockout policy in an authentication system?
Account lockout policies temporarily or permanently disable an account after repeated failed authentication attempts, making brute-force and password-spraying attacks impractical.
5. Which document type establishes the specific steps an operator must follow when acquiring a lymphocyte subset panel, ensuring reproducibility?
A Standard Operating Procedure defines step-by-step instructions for a specific assay, ensuring all operators perform it the same way.
6. In mass cytometry (CyTOF), what replaces fluorescent labels?
Mass cytometry uses antibodies conjugated to heavy metal isotopes detected by time-of-flight mass spectrometry, eliminating spectral overlap limitations.