INBDE Pharmacology and Pain Management 3

Question 1

Which drug interaction is most concerning when prescribing metronidazole?

Accepted Answer

Warfarin — increased anticoagulant effect

Answer

Metronidazole inhibits CYP2C9, reducing warfarin metabolism and significantly increasing INR, raising the risk of bleeding.

Question 2

Nitrous oxide/oxygen sedation is contraindicated in which patient?

Accepted Answer

A patient with chronic obstructive pulmonary disease (COPD)

Answer

Patients with COPD rely on hypoxic drive; supplemental oxygen via nitrous oxide sedation can suppress their respiratory drive and cause respiratory depression.

Question 3

Naloxone is the reversal agent for which class of drugs?

Accepted Answer

Opioids

Answer

Naloxone is a competitive opioid receptor antagonist that rapidly reverses respiratory depression, sedation, and analgesia caused by opioid overdose.

Question 4

Which medication used for oral sedation has the highest risk of paradoxical excitation in children?

Accepted Answer

Midazolam

Answer

Midazolam can cause paradoxical reactions (agitation, combativeness, increased anxiety) in approximately 1–15% of pediatric patients.

Question 5

Penicillin V potassium is classified as which type of antibiotic?

Accepted Answer

Beta-lactam

Answer

Penicillin V is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

INBDE - Integrated National Board Dental Exam Practice Test

INBDE - Integrated National Board Dental Exam Practice Test

INBDE Pharmacology and Pain Management 3