INBDE Oral Medicine and Oral Pathology 1 — Questions and Answers
Question 1: A 45-year-old patient presents with a white patch on the lateral border of the tongue that cannot be wiped off. Biopsy reveals epithelial dysplasia. What is the most appropriate diagnosis?
- Candidiasis
- Leukoplakia (Correct answer)
- Lichen planus
- Leukoedema
Correct answer: Leukoplakia
Leukoplakia is a clinical term for a white patch that cannot be wiped off and has no other identifiable cause; dysplasia on biopsy confirms its premalignant potential.
Question 2: Which type of ameloblastoma is most commonly found in the posterior mandible and is characterized by islands of odontogenic epithelium within a fibrous stroma?
- Unicystic ameloblastoma
- Peripheral ameloblastoma
- Solid/multicystic ameloblastoma (Correct answer)
- Desmoplastic ameloblastoma
Correct answer: Solid/multicystic ameloblastoma
The solid/multicystic (conventional) ameloblastoma is the most common type, arising predominantly in the posterior mandible with classic histological patterns including follicular and plexiform subtypes.
Question 3: A patient with HIV presents with painless, bluish-purple nodules on the hard palate. What is the most likely diagnosis?
- Bacillary angiomatosis
- Kaposi's sarcoma (Correct answer)
- Necrotizing ulcerative periodontitis
- Hairy leukoplakia
Correct answer: Kaposi's sarcoma
Kaposi's sarcoma is an AIDS-defining malignancy commonly presenting as blue-purple vascular lesions on the palate in HIV-infected individuals.
Question 4: A radiolucent lesion associated with the crown of an unerupted tooth is found on radiograph of a 20-year-old. Histology shows a thin epithelial lining with no dysplasia. What is the diagnosis?
- Odontogenic keratocyst
- Dentigerous cyst (Correct answer)
- Lateral periodontal cyst
- Calcifying odontogenic cyst
Correct answer: Dentigerous cyst
A dentigerous cyst (follicular cyst) is the most common developmental odontogenic cyst, enclosing the crown of an unerupted tooth at the cementoenamel junction.
Question 5: Erythema multiforme most commonly affects young adults and is characterized by which pathognomonic skin lesion?
- Nikolsky's sign
- Target (iris) lesion (Correct answer)
- Wickham's striae
- Koebner phenomenon
Correct answer: Target (iris) lesion
The target or iris lesion — concentric rings of erythema — is the hallmark cutaneous lesion of erythema multiforme.
Question 6: Which salivary gland tumor is most common overall and is characterized by a biphasic histology with both epithelial and mesenchymal-like components?
- Warthin's tumor
- Pleomorphic adenoma (Correct answer)
- Mucoepidermoid carcinoma
- Adenoid cystic carcinoma
Correct answer: Pleomorphic adenoma
Pleomorphic adenoma (mixed tumor) is the most common salivary gland neoplasm, characterized by a mixture of epithelial cells and chondromyxoid stroma.
Question 7: A 35-year-old female presents with bilateral parotid swelling, dry eyes, and dry mouth. What autoimmune condition should be suspected?
- Systemic lupus erythematosus
- Sjogren's syndrome (Correct answer)
- Sarcoidosis
- Rheumatoid arthritis
Correct answer: Sjogren's syndrome
Sjogren's syndrome is an autoimmune exocrinopathy presenting with bilateral parotid enlargement, xerostomia, and keratoconjunctivitis sicca (dry eyes).
INBDE Oral Medicine and Oral Pathology 1
A 45-year-old patient presents with a white patch on the lateral border of the tongue that cannot be wiped off.
Biopsy reveals epithelial dysplasia.
What is the most appropriate diagnosis?