Canine Internal Medicine Flashcards
7 cards from real ICVA practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Canine Internal Medicine flashcards as text
A 10-year-old neutered male dog presents with weight loss, ravenous appetite, and diarrhea. A cranial abdominal mass is palpated. Ultrasound shows a hypoechoic pancreatic mass. The most likely diagnosis is:
Answer: Insulinoma
Insulinoma is the most common functional pancreatic tumor in dogs, causing hypoglycemia-driven polyphagia, weakness, and seizures.
Which serologic test is used to confirm chronic Ehrlichia canis infection in a thrombocytopenic dog?
Answer: IFA for E. canis antibodies
IFA for Ehrlichia canis antibodies is the serologic standard; titers ≥1:80 with compatible clinical signs confirm exposure.
A dog with dilated cardiomyopathy (DCM) is started on pimobendan. What is the primary mechanism of action of this drug?
Answer: Calcium sensitization and phosphodiesterase III inhibition increasing contractility and causing vasodilation
Pimobendan is a positive inotrope and vasodilator that sensitizes troponin C to calcium and inhibits PDE III, improving cardiac output.
Which urine sediment finding is pathognomonic for ethylene glycol toxicity in a dog?
Answer: Calcium oxalate monohydrate crystals
Calcium oxalate monohydrate (hippurate-shaped) crystals in urine are pathognomonic for ethylene glycol poisoning, reflecting oxalic acid metabolite deposition.
A dog with protein-losing enteropathy (PLE) has hypoalbuminemia, hypocholesterolemia, and hypocalcemia. Which intestinal disease most commonly causes PLE in dogs?
Answer: Intestinal lymphangiectasia
Intestinal lymphangiectasia causes dilation and rupture of lymphatics, leading to profound loss of protein, lipids, and fat-soluble vitamins into the gut.
In a dog with suspected immune-mediated thrombocytopenia (IMT), which platelet count threshold typically warrants immediate immunosuppressive therapy to prevent spontaneous hemorrhage?
Answer: <30,000/µL
Platelet counts below 30,000/µL carry significant risk of spontaneous bleeding and generally prompt initiation of immunosuppressive treatment.
A dog on trimethoprim-sulfadiazine for 6 weeks develops keratoconjunctivitis sicca (KCS). Which mechanism explains this adverse effect?
Answer: Inhibition of carbonic anhydrase in the lacrimal gland
Sulfonamides inhibit carbonic anhydrase in the lacrimal gland epithelium, reducing aqueous tear production and causing KCS.