Pharmacology Pharmacokinetics

Question 1

Which of the following processes is primarily responsible for the movement of a drug from its site of administration into the bloodstream?

Accepted Answer

Absorption

Answer

Distribution

Answer

Metabolism

Answer

Excretion

Question 2

The term "bioavailability" refers to:

Accepted Answer

The percentage of the administered dose that reaches systemic circulation unchanged

Answer

The amount of drug absorbed and available at the target tissue

Answer

The volume of distribution of the drug

Answer

The rate of drug elimination from the body

Question 3

Which organ is most responsible for the metabolism of drugs?

Accepted Answer

Liver

Answer

Kidneys

Answer

Stomach

Answer

Lungs

Question 4

What does "first-pass metabolism" refer to?

Accepted Answer

The metabolism of a drug by the liver before it reaches systemic circulation

Answer

The process of drug excretion through the kidneys

Answer

The rapid metabolism of a drug in the stomach

Answer

The binding of a drug to plasma proteins

Question 5

A drug with a half-life of 4 hours will have approximately 25% of the initial dose remaining in the body after:

Accepted Answer

8 hours

Answer

2 hours

Answer

4 hours

Answer

12 hours