FREE DMD Oral Pathology and Diagnosis Questions and Answers

Question 1

A 45-year-old male presents with a painless, multilocular radiolucency in the posterior mandible, discovered on a routine panoramic radiograph.
The lesion exhibits a 'soap bubble' appearance.
Tooth resorption and cortical expansion are noted.
Which of the following is the most likely diagnosis?

Accepted Answer

Ameloblastoma

Answer

Odontogenic Keratocyst (OKC)

Answer

Central Giant Cell Granuloma (CGCG)

Answer

Cherubism

Question 2

A 60-year-old female patient complains of painful oral erosions and blisters that have been present for several months. Intraoral examination reveals irregular, fragile bullae and widespread ulcerations on the buccal mucosa and palate. A positive Nikolsky's sign is elicited. Histopathological examination of a biopsy specimen is most likely to show:

Accepted Answer

Intraepithelial separation (acantholysis) just above the basal cell layer

Answer

Subepidermal separation with an eosinophil-rich infiltrate

Answer

Hyperkeratosis with a band-like lymphocytic infiltrate

Answer

Acanthosis with elongated rete ridges and Munro's microabscesses

Question 3

Which of the following oral lesions has the highest potential for malignant transformation?

Accepted Answer

Erythroplakia

Answer

Homogeneous Leukoplakia

Answer

Oral Lichen Planus

Answer

Oral Hairy Leukoplakia

Question 4

A 22-year-old male is referred by his orthodontist due to multiple impacted supernumerary teeth and several dense, well-defined radiopacities in the mandible and maxilla seen on a panoramic radiograph. The patient also has multiple sebaceous cysts on his back. These findings are highly suggestive of which systemic condition?

Accepted Answer

Gardner Syndrome

Answer

Cleidocranial Dysplasia

Answer

Sjögren's Syndrome

Answer

Cherubism

Question 5

A 55-year-old female patient presents with severe xerostomia, rampant cervical and root caries, and a fissured tongue. She also complains of dry eyes. A labial salivary gland biopsy is performed to confirm a suspected diagnosis. Which histologic finding would be most characteristic of Sjögren's Syndrome?

Accepted Answer

Focal lymphocytic sialadenitis with a focus score of ≥1

Answer

Squamous metaplasia of ductal epithelium

Answer

Fibrosis and fatty infiltration of the acini

Answer

Mucous extravasation phenomenon with granulation tissue

Question 6

A patient presents with asymptomatic, white, corrugated lesions along the lateral borders of the tongue that cannot be wiped off. The patient is known to be immunosuppressed. Which of the following is the most likely diagnosis?

Accepted Answer

Oral Hairy Leukoplakia

Answer

Candidiasis (Thrush)

Answer

Lichen Planus

Answer

Frictional Keratosis