Core Knowledge and Fundamentals Flashcards
7 cards from real FRACGP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Core Knowledge and Fundamentals flashcards as text
A 5-year-old boy presents with a widespread vesicular rash, fever, and intense pruritus. His mother reports he received the first dose of varicella vaccine 2 months ago. The MOST appropriate next step is:
Answer: Symptomatic treatment and advise isolation until all lesions crust
Breakthrough varicella in vaccinated individuals is usually mild and self-limiting; management is symptomatic with isolation until lesions crust to prevent spread.
Which spirometry pattern is MOST consistent with a diagnosis of asthma that responds to bronchodilator therapy?
Answer: Obstructive pattern with ≥12% and 200 mL improvement in FEV₁ after bronchodilator
Asthma is confirmed by a reversible obstructive defect showing ≥12% and ≥200 mL increase in FEV₁ post-bronchodilator according to GINA criteria.
A 68-year-old woman with type 2 diabetes and CKD stage 3b (eGFR 32 mL/min/1.73m²) needs glucose-lowering therapy adjustment. Which agent should be STOPPED or avoided at this eGFR?
Answer: Metformin
Metformin is contraindicated when eGFR falls below 30 and should be used with caution below 45 mL/min due to lactic acidosis risk.
A 28-year-old woman presents at 10 weeks gestation with nausea, vomiting, and a uterus larger than dates. Her β-hCG is markedly elevated and ultrasound shows a 'snowstorm' appearance. The MOST likely diagnosis is:
Answer: Complete hydatidiform mole
A complete hydatidiform mole presents with a markedly elevated β-hCG, snowstorm ultrasound appearance, and uterus large for dates due to trophoblastic proliferation.
In the management of an acute gout flare in a patient with CKD stage 4, which of the following is the PREFERRED first-line anti-inflammatory treatment?
Answer: Low-dose colchicine (with dose adjustment) or prednisolone
NSAIDs are contraindicated in advanced CKD; low-dose colchicine (renally adjusted) or oral corticosteroids are preferred for acute gout in this setting.
A GP is reviewing a 55-year-old man with newly diagnosed hypertension. His BP is 158/96 mmHg on two readings. He has no other comorbidities. According to Australian guidelines, what is the FIRST recommended action?
Answer: Lifestyle modification for 3–6 months before pharmacotherapy if no end-organ damage
For stage 1–2 hypertension without end-organ damage, Australian guidelines recommend a trial of lifestyle modification (3–6 months) before initiating pharmacotherapy.
Which of the following correctly describes the mechanism of action of bupropion when used for smoking cessation?
Answer: Noradrenaline and dopamine reuptake inhibition reducing nicotine cravings
Bupropion inhibits noradrenaline and dopamine reuptake, reducing craving and withdrawal symptoms by modulating the reward pathway involved in nicotine dependence.