FPGEE Pharmacy Practice 4

Question 1

A patient with renal impairment (CrCl 20 mL/min) is prescribed vancomycin. How should the dosing be adjusted?

Accepted Answer

Decrease dose or increase dosing interval

Answer

Increase dose frequency

Answer

No adjustment needed

Answer

Switch to oral route only

Question 2

Which immunization is CONTRAINDICATED in a patient who is 28 weeks pregnant?

Accepted Answer

MMR

Answer

Influenza (inactivated)

Answer

Tdap

Answer

COVID-19 mRNA vaccine

Question 3

A patient fills a prescription for sildenafil and also takes isosorbide mononitrate. What is the primary concern?

Accepted Answer

Severe hypotension due to additive vasodilation

Answer

Increased risk of priapism

Answer

Reduced efficacy of sildenafil

Answer

Increased risk of QT prolongation

Question 4

According to USP <797>, what is the beyond-use date (BUD) for a compounded sterile preparation assigned Category 1?

Accepted Answer

12 hours at controlled room temperature or 24 hours refrigerated

Answer

12 hours at room temperature or 24 hours refrigerated

Answer

24 hours at room temperature or 72 hours refrigerated

Answer

30 days refrigerated

Question 5

A pharmacist is reviewing a medication profile and notices a patient on methotrexate is also prescribed trimethoprim-sulfamethoxazole (TMP-SMX). What is the clinical concern?

Accepted Answer

Both drugs inhibit dihydrofolate reductase, increasing methotrexate toxicity

Answer

TMP-SMX increases methotrexate renal clearance

Answer

TMP-SMX reduces methotrexate oral bioavailability

Answer

No clinically relevant interaction exists

Question 6

A pharmacist counsels a patient starting levothyroxine. When is the BEST time to take this medication?

Accepted Answer

30–60 minutes before breakfast on an empty stomach

Answer

With breakfast to enhance absorption

Answer

At bedtime with a full glass of water

Answer

With the largest meal of the day

Question 7

Which measurement is used to assess insulin dosing effectiveness in a diabetic patient over the past 2–3 months?

Accepted Answer

HbA1c

Answer

Fasting plasma glucose

Answer

Random blood glucose

Answer

C-peptide level