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Pharmacy Practice Flashcards

7 cards from real FPGEE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient with renal impairment (CrCl 20 mL/min) is prescribed vancomycin. How should the dosing be adjusted?

    Answer: Decrease dose or increase dosing interval

    Vancomycin is primarily renally eliminated; reduced CrCl requires dose reduction or extended dosing intervals to prevent accumulation and nephrotoxicity.

  2. Which immunization is CONTRAINDICATED in a patient who is 28 weeks pregnant?

    Answer: MMR

    MMR is a live attenuated vaccine and is contraindicated during pregnancy due to theoretical risk of fetal infection.

  3. A patient fills a prescription for sildenafil and also takes isosorbide mononitrate. What is the primary concern?

    Answer: Severe hypotension due to additive vasodilation

    Both sildenafil (PDE-5 inhibitor) and nitrates cause vasodilation; combined use produces severe, potentially fatal hypotension.

  4. According to USP , what is the beyond-use date (BUD) for a compounded sterile preparation assigned Category 1?

    Answer: 12 hours at controlled room temperature or 24 hours refrigerated

    USP Category 1 CSPs have a BUD of 12 hours at controlled room temperature (CRT) or 24 hours refrigerated.

  5. A pharmacist is reviewing a medication profile and notices a patient on methotrexate is also prescribed trimethoprim-sulfamethoxazole (TMP-SMX). What is the clinical concern?

    Answer: Both drugs inhibit dihydrofolate reductase, increasing methotrexate toxicity

    TMP-SMX and methotrexate both inhibit dihydrofolate reductase, causing additive antifolate toxicity (myelosuppression, mucositis).

  6. A pharmacist counsels a patient starting levothyroxine. When is the BEST time to take this medication?

    Answer: 30–60 minutes before breakfast on an empty stomach

    Levothyroxine should be taken 30–60 minutes before breakfast on an empty stomach to maximize absorption, as food reduces bioavailability.

  7. Which measurement is used to assess insulin dosing effectiveness in a diabetic patient over the past 2–3 months?

    Answer: HbA1c

    HbA1c reflects average blood glucose over the prior 2–3 months by measuring glycosylated hemoglobin, providing a long-term efficacy assessment.