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FPGEE MCQ Exam Flashcards

7 cards from real FPGEE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A pharmacist receives a prescription for oxycodone 5 mg #30. The DEA schedule of oxycodone requires how many days' supply maximum per prescription in most US states?

    Answer: No federal day-supply limit exists for Schedule II

    Federally, the DEA does not impose a day-supply limit on Schedule II prescriptions; however, individual states may set their own limits.

  2. Which mechanism explains the therapeutic action of metformin in type 2 diabetes?

    Answer: Activates AMPK, reducing hepatic glucose output

    Metformin primarily activates AMP-activated protein kinase (AMPK), suppressing hepatic gluconeogenesis and glycogenolysis to lower blood glucose.

  3. A patient on warfarin begins taking high-dose vitamin E supplements. What is the expected effect on INR?

    Answer: Increased INR due to inhibition of vitamin K-dependent clotting factors

    High-dose vitamin E impairs vitamin K–dependent carboxylation of clotting factors II, VII, IX, and X, potentiating warfarin's anticoagulant effect and raising INR.

  4. Which isomer of albuterol is responsible for its bronchodilatory therapeutic effect?

    Answer: R-albuterol (levalbuterol)

    R-albuterol (levalbuterol) is the eutomer that binds beta-2 receptors and causes bronchodilation; S-albuterol may contribute to bronchoconstriction.

  5. A patient with Parkinson's disease taking levodopa/carbidopa develops end-of-dose wearing off. Which add-on agent BEST extends levodopa effect?

    Answer: Entacapone (COMT inhibitor)

    Entacapone inhibits COMT, preventing peripheral breakdown of levodopa and extending its duration of action to reduce wearing-off.

  6. What is the primary mechanism of resistance to beta-lactam antibiotics in MRSA?

    Answer: Altered penicillin-binding protein (PBP2a) encoded by mecA gene

    MRSA resistance is mediated by mecA gene–encoded PBP2a, a modified penicillin-binding protein with low affinity for all beta-lactam antibiotics.

  7. A 28-year-old woman with epilepsy who wants to become pregnant is on valproic acid. Which alternative AED is preferred to minimize teratogenicity?

    Answer: Lamotrigine

    Lamotrigine has the lowest teratogenic risk among common AEDs and is preferred for women of childbearing age when seizure control allows.