CTP Certified Transplant Preservationist exam – how deep do the preservation solution questions actually go?
I've been working in organ procurement for three years and my OPO is encouraging me to sit for the CTP exam this cycle. I'm genuinely uncertain about the depth of knowledge the exam expects on preservation solution chemistry and machine perfusion protocols, since my day-to-day work involves following established protocols rather than understanding the underlying physiology at a granular level. I want to know if I need to get into the biochemistry weeds or if the exam tests more procedural and clinical knowledge.
I started studying about five weeks ago and I'm putting in roughly two hours on weekdays and five or six hours on weekends. My practice scores have been hovering around 66–70%, which doesn't feel like a comfortable margin. The procurement logistics and donor management sections feel very familiar from work, but the preservation science questions are hitting me harder than I expected. I've gone through about 300 practice questions so far and the preservation solution composition questions in particular are where I keep losing points.
I'd really like to hear from people who've passed the CTP recently about what proportion of the exam felt like it was testing protocol execution versus underlying science. My OPO has people who passed two and four years ago but transplant science has moved pretty fast, especially with normothermic machine perfusion becoming more common. Not sure if their advice is still current for the exam as it's structured today.
66–70% with five weeks left is workable but not comfortable. I'd shift your study approach to targeted drilling on preservation science specifically rather than balanced review across all domains. Get to 75–78% on practice sets covering that material before you go back to doing mixed topic sets.
The donor management and brain death evaluation content is very procedurally tested — those sections align well with OPO work experience. Lean on those as your reliable point scorers while you shore up the preservation science gaps. Going in knowing certain sections are locked in makes a real difference mentally on test day.
The CTP exam does go into preservation solution science at a level that's deeper than just following protocols. You need to understand why specific components are in the solutions and what each one does physiologically. UW solution composition, HTK rationale, and basic cold ischemia mechanisms are all fair game. Give those at least two full dedicated study weeks.
I passed last year and the machine perfusion content was more prominent than it was in older exam versions based on what colleagues described. Normothermic regional perfusion and hypothermic machine perfusion basics are both worth studying, not just static cold storage. Your OPO contacts from four years ago probably won't have seen that material with the same depth.
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