Family Practice Exam Preventive Medicine 4 — Questions and Answers
Question 1: Which vaccine is contraindicated in a 32-year-old woman who is 10 weeks pregnant?
- Inactivated influenza vaccine
- Tdap vaccine
- MMR vaccine (Correct answer)
- Hepatitis B vaccine
Correct answer: MMR vaccine
MMR is a live attenuated vaccine and is contraindicated during pregnancy due to theoretical risk of fetal infection; it should be given postpartum.
Question 2: A 45-year-old woman with no family history has a routine Pap smear with HPV co-test. Her result is HPV-negative with normal cytology. What is the recommended rescreening interval?
- 1 year
- 3 years
- 5 years (Correct answer)
- 10 years
Correct answer: 5 years
Women aged 30–65 who undergo co-testing (Pap + HPV) with both results negative may be screened every 5 years per ACS/USPSTF guidelines.
Question 3: What is the recommended screening interval for prediabetes and type 2 diabetes screening in asymptomatic adults aged 35–70 who are overweight or obese, per USPSTF?
- Annually
- Every 2 years
- Every 3 years (Correct answer)
- Every 5 years
Correct answer: Every 3 years
USPSTF recommends screening every 3 years for prediabetes/type 2 diabetes in overweight or obese adults aged 35–70 when results are normal.
Question 4: Which counseling intervention does the USPSTF recommend as part of primary prevention for sexually active adolescents and adults at increased risk for STIs?
- Mandatory STI testing every 6 months
- Intensive behavioral counseling (Correct answer)
- Prophylactic antibiotics before sexual activity
- Pelvic exam annually
Correct answer: Intensive behavioral counseling
USPSTF recommends intensive behavioral counseling for all sexually active adolescents and adults at increased risk for STIs to reduce infection rates.
Question 5: Aspirin use for primary prevention of cardiovascular disease in adults aged 40–59 with ≥10% 10-year CVD risk is classified as which USPSTF grade?
- Grade A — strongly recommended
- Grade B — recommended
- Grade C — individualized decision (Correct answer)
- Grade D — recommended against
Correct answer: Grade C — individualized decision
USPSTF gives a Grade C recommendation for aspirin in adults 40–59 with ≥10% CVD risk, meaning clinicians should offer it selectively based on individual patient circumstances.
Question 6: Newborn screening in the United States routinely tests for phenylketonuria (PKU) primarily to prevent which complication?
- Neonatal seizures
- Intellectual disability (Correct answer)
- Congenital heart defects
- Hypothyroidism
Correct answer: Intellectual disability
Early detection of PKU allows immediate dietary phenylalanine restriction, preventing the accumulation that leads to severe intellectual disability.
Question 7: A 70-year-old male who smoked 25 pack-years and quit 20 years ago presents for a health maintenance visit. Should he receive USPSTF low-dose CT lung cancer screening?
- Yes, because he is 70 and ever smoked
- No, because he quit more than 15 years ago (Correct answer)
- Yes, if he has any respiratory symptoms
- No, because he is over 80
Correct answer: No, because he quit more than 15 years ago
USPSTF criteria require quitting within the past 15 years; since this patient quit 20 years ago, he no longer meets eligibility for lung cancer screening.
Which vaccine is contraindicated in a 32-year-old woman who is 10 weeks pregnant?