ENT Head and Neck Oncology Flashcards

What is the most common malignant tumor of the parotid gland?

Answer: Mucoepidermoid carcinoma

Mucoepidermoid carcinoma is the most common malignant salivary gland tumor overall and the most frequent malignancy of the parotid gland, classified as low, intermediate, or high grade.

Nasopharyngeal carcinoma is strongly associated with which viral infection?

Answer: Epstein-Barr virus (EBV)

Epstein-Barr virus (EBV) is strongly associated with nasopharyngeal carcinoma, particularly the undifferentiated WHO type III subtype endemic in Southeast Asia and southern China.

Which is the most common site of squamous cell carcinoma within the oral cavity?

Answer: Lateral border of the tongue

The lateral border of the tongue is the most common site for oral cavity squamous cell carcinoma, accounting for approximately 40% of all oral cavity cancers.

What is the preferred treatment for T1N0 glottic (true vocal cord) carcinoma?

Answer: Radiation therapy or transoral laser excision

Early-stage T1N0 glottic carcinoma has excellent cure rates with either radiation therapy or transoral laser microsurgery, both of which preserve voice function.

Perineural invasion in head and neck cancers is most classically associated with which salivary gland tumor type?

Answer: Adenoid cystic carcinoma

Adenoid cystic carcinoma has a strong predilection for perineural invasion, causing skip lesions along nerve sheaths and contributing to its high rate of late recurrence.

Which is the most common benign tumor of the parotid gland?

Answer: Pleomorphic adenoma

Pleomorphic adenoma (benign mixed tumor) is the most common salivary gland neoplasm, accounting for approximately 70% of all parotid gland tumors.