Dermatologist Certificate General 4

Question 1

Which of the following best describes the mechanism of action of isotretinoin in treating acne?

Accepted Answer

Reduces sebaceous gland size and sebum production

Answer

Isotretinoin permanently reduces sebaceous gland size by up to 90%, dramatically decreasing sebum production and normalizing follicular keratinization.

Question 2

What is the first-line treatment for onychomycosis confirmed by positive fungal culture?

Accepted Answer

Oral terbinafine

Answer

Oral terbinafine for 12 weeks is first-line for toenail onychomycosis due to its high cure rate and fungicidal mechanism against dermatophytes.

Question 3

A patient presents with targetoid lesions after starting trimethoprim-sulfamethoxazole. Mucosal involvement affects two sites. What is the diagnosis?

Accepted Answer

Stevens-Johnson syndrome

Answer

Stevens-Johnson syndrome involves mucosal involvement at ≥2 sites with epidermal detachment affecting <10% of body surface area, often triggered by drugs.

Question 4

Dermatitis herpetiformis is characterized by deposits of which immunoglobulin in the dermal papillae?

Accepted Answer

IgA

Answer

Dermatitis herpetiformis shows granular IgA deposits in the dermal papillae on direct immunofluorescence, associated with celiac disease.

Question 5

Which ABCDE criterion for melanoma evaluation stands for 'Evolution'?

Accepted Answer

The lesion has changed over time

Answer

The 'E' in ABCDE stands for Evolution — any change in size, shape, color, or a new symptom such as bleeding is a warning sign of melanoma.

Dermatologist Certificate Practice Test

Dermatologist Certificate Practice Test

Dermatologist Certificate General 4