Dermatologist Certificate General 2

Question 1

Which layer of the epidermis is responsible for cell division and renewal?

Accepted Answer

Stratum basale

Answer

The stratum basale contains mitotically active keratinocytes that continuously divide to renew the epidermis.

Question 2

A patient presents with discrete, flat-topped, polygonal, violaceous papules on the wrists. What is the most likely diagnosis?

Accepted Answer

Lichen planus

Answer

Lichen planus classically presents with the '6 P's': pruritic, planar, polygonal, purple papules and plaques.

Question 3

Which immunoglobulin is primarily found at the dermal-epidermal junction in bullous pemphigoid?

Accepted Answer

IgG

Answer

Bullous pemphigoid is characterized by IgG autoantibodies targeting BP180 and BP230 antigens at the dermal-epidermal junction.

Question 4

A child presents with a 'strawberry tongue,' desquamating rash, and perioral pallor. What organism is responsible?

Accepted Answer

Group A Streptococcus

Answer

Scarlet fever is caused by Group A Streptococcus producing erythrogenic toxins, leading to the classic rash and strawberry tongue.

Question 5

Which dermatoscopic structure is most associated with melanoma?

Accepted Answer

Atypical pigment network

Answer

An atypical (irregular) pigment network with variable thickness and abrupt termination at the periphery is a key dermoscopic feature of melanoma.

Dermatologist Certificate Practice Test