Dermatologist Certificate Dermatologist Certificate MCQ 5

Question 1

Which biologic drug class is approved for moderate-to-severe plaque psoriasis and works by inhibiting IL-17A?

Accepted Answer

IL-17A inhibitors

Answer

Secukinumab and ixekizumab are IL-17A inhibitors approved for moderate-to-severe plaque psoriasis with high efficacy.

Question 2

A patient presents with grouped vesicles on an erythematous base along a unilateral thoracic dermatome. Which antiviral is first-line?

Accepted Answer

Valacyclovir 1000 mg TID

Answer

Valacyclovir 1000 mg three times daily for 7 days is preferred for herpes zoster due to improved bioavailability over acyclovir.

Question 3

Pityriasis versicolor is caused by which organism?

Accepted Answer

Pityrosporum orbiculare (Malassezia globosa)

Answer

Pityriasis versicolor is most often caused by Malassezia globosa (formerly classified as Pityrosporum orbiculare), a lipophilic yeast.

Question 4

Which histologic finding is pathognomonic for lichen planus?

Accepted Answer

Max-Joseph spaces with saw-tooth rete ridges

Answer

Lichen planus shows vacuolar interface dermatitis with Max-Joseph spaces, saw-tooth rete ridges, and a band-like lymphocytic infiltrate.

Question 5

A 70-year-old woman has tense bullae on uninflamed skin of the thighs and lower abdomen. DIF shows linear IgG and C3 at the dermoepidermal junction. What is the diagnosis?

Accepted Answer

Bullous pemphigoid

Answer

Bullous pemphigoid presents with tense subepidermal bullae and linear IgG/C3 at the BMZ on DIF, targeting BP180 and BP230.

Dermatologist Certificate Practice Test

Dermatologist Certificate Practice Test

Dermatologist Certificate Dermatologist Certificate MCQ 5