Dermatologist Certificate Dermatologist Certificate MCQ 4

Question 1

A patient with HIV presents with diffuse brownish-red macules and papules on the palms and soles. Which diagnosis should be considered first?

Accepted Answer

Secondary syphilis

Answer

Palm and sole involvement is a hallmark of secondary syphilis, which must be ruled out in any sexually active or immunocompromised patient.

Question 2

Which finding on dermoscopy is most characteristic of a melanoma?

Accepted Answer

Atypical pigment network with regression

Answer

An atypical (irregular/broadened) pigment network with areas of regression is a major dermoscopic feature suggestive of melanoma.

Question 3

A 25-year-old woman develops a butterfly-shaped malar rash after sun exposure. ANA is positive. Which skin finding would further support systemic lupus erythematosus?

Accepted Answer

Photosensitive malar rash sparing the nasolabial folds

Answer

The malar rash of SLE classically spares the nasolabial folds, which distinguishes it from rosacea and seborrheic dermatitis.

Question 4

Which gene is most commonly mutated in familial melanoma?

Accepted Answer

CDKN2A

Answer

CDKN2A (encoding p16/INK4a) is the most frequently mutated gene in hereditary melanoma-prone families.

Question 5

A teenager presents with open and closed comedones without inflammatory lesions. Which topical agent is most appropriate as first-line monotherapy?

Accepted Answer

Topical tretinoin

Answer

Topical retinoids like tretinoin are first-line for comedonal acne because they normalize follicular keratinization.

Dermatologist Certificate Practice Test

Dermatologist Certificate Practice Test

Dermatologist Certificate Dermatologist Certificate MCQ 4