Dermatologist Certificate Dermatologist Certificate MCQ 3

Question 1

Which of the following is the first-line treatment for onychomycosis caused by dermatophytes?

Accepted Answer

Oral terbinafine

Answer

Oral terbinafine is the first-line treatment for dermatophyte onychomycosis due to its high cure rates and fungicidal activity.

Question 2

A 60-year-old presents with a pearly, rolled border nodule on the nose with telangiectasias and central ulceration. What is the most likely diagnosis?

Accepted Answer

Basal cell carcinoma

Answer

A pearly nodule with rolled borders, telangiectasias, and central ulceration on sun-exposed skin of an older patient is classic for nodular basal cell carcinoma.

Question 3

Which autoantibody is most specifically associated with pemphigus vulgaris?

Accepted Answer

Anti-desmoglein 3

Answer

Pemphigus vulgaris is caused by IgG antibodies against desmoglein 3, leading to acantholysis and suprabasal blisters.

Question 4

Nikolsky's sign, where lateral pressure causes the skin to slide and blister, is positive in which condition?

Accepted Answer

Pemphigus vulgaris

Answer

Nikolsky's sign is positive in pemphigus vulgaris due to the fragile suprabasal cleavage plane caused by desmoglein 3 autoantibodies.

Question 5

Which topical calcineurin inhibitor is approved for use in children as young as 2 years old for atopic dermatitis?

Accepted Answer

Tacrolimus 0.03%

Answer

Tacrolimus 0.03% ointment is approved for children aged 2–15 years, while the 0.1% formulation is reserved for adults.

Dermatologist Certificate Practice Test

Dermatologist Certificate Practice Test

Dermatologist Certificate Dermatologist Certificate MCQ 3