Trivia Flashcards
7 cards from real Dermatologist Certificate practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Trivia flashcards as text
What term describes the genetic skin disorder characterized by absent or reduced melanin production due to tyrosinase deficiency?
Answer: Oculocutaneous albinism
Oculocutaneous albinism results from mutations in genes such as TYR (tyrosinase), leading to absent or severely reduced melanin in skin, hair, and eyes.
The phrase 'herald patch' is the classic initial presentation of which common self-limited skin eruption?
Answer: Pityriasis rosea
Pityriasis rosea classically begins with a single large 'herald patch' followed days to weeks later by a widespread Christmas-tree pattern eruption.
Which vitamin, when severely deficient, causes pellagra with its classic triad of dermatitis, diarrhea, and dementia?
Answer: Niacin (B3)
Pellagra results from niacin (vitamin B3) or tryptophan deficiency; the skin shows a photosensitive dermatitis in sun-exposed areas called casal necklace.
Which skin sign—yellowing of the sclerae and skin—most commonly indicates which underlying metabolic process?
Answer: Elevated serum bilirubin from hepatic or hemolytic disease
True jaundice with scleral icterus reflects hyperbilirubinemia (>2–3 mg/dL) from liver disease or hemolysis, not dietary carotenoids.
The Darier sign, elicited by stroking a lesion causing it to urticate and become raised, is pathognomonic for which condition?
Answer: Mastocytosis (urticaria pigmentosa)
Darier sign reflects mast cell degranulation in urticaria pigmentosa (cutaneous mastocytosis) upon physical stroking of the lesion.
Which anatomic structure marks the junction between the epidermis and dermis and plays a key role in anchoring the two layers?
Answer: Basement membrane zone
The basement membrane zone (dermal-epidermal junction) contains hemidesmosomes, laminin, and type IV collagen that anchor the epidermis to the dermis.
What is the name of the embryological process by which melanocytes migrate from the neural crest to the epidermis?
Answer: Neural crest cell migration
Melanocytes originate from neural crest cells that migrate during embryogenesis into the epidermis, dermis, and other tissues.
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