General Flashcards
7 cards from real Dermatologist Certificate practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 General flashcards as text
Which of the following best describes the mechanism of action of isotretinoin in treating acne?
Answer: Reduces sebaceous gland size and sebum production
Isotretinoin permanently reduces sebaceous gland size by up to 90%, dramatically decreasing sebum production and normalizing follicular keratinization.
What is the first-line treatment for onychomycosis confirmed by positive fungal culture?
Answer: Oral terbinafine
Oral terbinafine for 12 weeks is first-line for toenail onychomycosis due to its high cure rate and fungicidal mechanism against dermatophytes.
A patient presents with targetoid lesions after starting trimethoprim-sulfamethoxazole. Mucosal involvement affects two sites. What is the diagnosis?
Answer: Stevens-Johnson syndrome
Stevens-Johnson syndrome involves mucosal involvement at ≥2 sites with epidermal detachment affecting <10% of body surface area, often triggered by drugs.
Dermatitis herpetiformis is characterized by deposits of which immunoglobulin in the dermal papillae?
Answer: IgA
Dermatitis herpetiformis shows granular IgA deposits in the dermal papillae on direct immunofluorescence, associated with celiac disease.
Which ABCDE criterion for melanoma evaluation stands for 'Evolution'?
Answer: The lesion has changed over time
The 'E' in ABCDE stands for Evolution — any change in size, shape, color, or a new symptom such as bleeding is a warning sign of melanoma.
Seborrheic dermatitis preferentially affects which areas?
Answer: Scalp, nasolabial folds, and central chest
Seborrheic dermatitis affects sebum-rich areas including the scalp, face (nasolabial folds, eyebrows), and upper trunk due to Malassezia overgrowth.
Which finding on histopathology is pathognomonic for psoriasis?
Answer: Munro microabscesses in the stratum corneum
Munro microabscesses — collections of neutrophils in the stratum corneum — are a pathognomonic histological feature of psoriasis.
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