Dermatologist Certificate Skin Disorders and Diagnosis

Question 1

Which skin condition is characterized by silvery-white plaques with well-defined borders most commonly found on the elbows and knees?

Accepted Answer

Psoriasis

Answer

Psoriasis presents as thick, silvery-white scaly plaques with sharply demarcated borders, classically on extensor surfaces like elbows and knees.

Question 2

What is the hallmark clinical feature of atopic dermatitis (eczema) in adults?

Accepted Answer

Lichenification and pruritus in flexural areas

Answer

Adult atopic dermatitis typically presents with lichenification and intense itching in flexural areas such as the antecubital and popliteal fossae.

Question 3

Which type of melanoma is most commonly found on the palms, soles, and nail beds?

Accepted Answer

Acral lentiginous melanoma

Answer

Acral lentiginous melanoma is the most common melanoma subtype in darker-skinned individuals and arises on acral surfaces including palms, soles, and subungual regions.

Question 4

What is the primary pathological finding in bullous pemphigoid?

Accepted Answer

IgG autoantibodies targeting BP180 and BP230 at the dermoepidermal junction

Answer

Bullous pemphigoid is caused by IgG autoantibodies against BP180 (collagen XVII) and BP230, proteins of the hemidesmosome at the dermoepidermal junction.

Question 5

Tzanck smear showing multinucleated giant cells is characteristic of which condition?

Accepted Answer

Herpes simplex or varicella-zoster infection

Answer

A positive Tzanck smear showing multinucleated giant cells is diagnostic of herpetic infections, including both herpes simplex virus and varicella-zoster virus.

Dermatologist Certificate Practice Test

Dermatologist Certificate Practice Test

Dermatologist Certificate Skin Disorders and Diagnosis