DEA DEA Pharmacology and Drug Effects 1

Question 1

What is the primary mechanism of action of opioids at the cellular level?

Accepted Answer

They bind to mu, kappa, and delta opioid receptors

Answer

Opioids primarily bind to mu, kappa, and delta opioid receptors in the central nervous system, reducing pain signal transmission.

Question 2

Which neurotransmitter is primarily responsible for cocaine's intense euphoric effects?

Accepted Answer

Dopamine

Answer

Cocaine blocks dopamine reuptake in the nucleus accumbens, causing a surge of dopamine that produces intense euphoria.

Question 3

What pharmacological term describes the need for increasing doses of a drug to achieve the same effect over time?

Accepted Answer

Tolerance

Answer

Tolerance occurs when the body adapts to a drug's presence, requiring progressively higher doses to achieve the original therapeutic or euphoric effect.

Question 4

Which drug class works primarily by enhancing GABA inhibitory activity at the GABA-A receptor?

Accepted Answer

Benzodiazepines

Answer

Benzodiazepines bind to GABA-A receptors and enhance the inhibitory effect of GABA, producing sedation, anxiolytic, and anticonvulsant effects.

Question 5

Which synthetic opioid is approximately 100 times more potent than morphine by weight?

Accepted Answer

Fentanyl

Answer

Fentanyl is approximately 100 times more potent than morphine, making it extremely dangerous even in microgram quantities and a leading driver of overdose deaths.

Drug Enforcement Administration (DEA) Practice Test

Drug Enforcement Administration (DEA) Practice Test

DEA DEA Pharmacology and Drug Effects 1