DAANCE Anesthetic Pharmacology 5

Question 1

Which of the following drugs is classified as a non-opioid analgesic that works centrally and is commonly used as premedication for dental sedation?

Accepted Answer

Acetaminophen

Answer

Acetaminophen is a centrally acting non-opioid analgesic used for premedication and multimodal analgesia in dental sedation protocols.

Question 2

The primary mechanism by which local anesthetics block nerve conduction is:

Accepted Answer

Binding to voltage-gated sodium channels in the inactivated state

Answer

Local anesthetics bind to voltage-gated sodium channels in their inactivated state, preventing sodium influx and halting action potential propagation.

Question 3

A patient receiving IV propofol sedation develops apnea. Which of the following best explains this adverse effect?

Accepted Answer

Propofol potentiates GABA-A receptors, depressing respiratory drive

Answer

Propofol enhances inhibitory GABA-A receptor activity, which at higher doses suppresses the brainstem respiratory center.

Question 4

Which local anesthetic is unique in that it is an ester with an amide linkage within the same molecule and is delivered in cartridges with epinephrine for dental use?

Accepted Answer

Articaine

Answer

Articaine is a hybrid molecule containing both an amide and an ester group, allowing it to be metabolized in plasma as well as in the liver.

Question 5

Methemoglobinemia is a known toxic complication associated with which local anesthetic?

Accepted Answer

Prilocaine

Answer

Prilocaine's metabolite ortho-toluidine oxidizes hemoglobin to methemoglobin, reducing oxygen-carrying capacity.

DAANCE - Dental Anesthesia Assistant National Certification Examination Practice Test

DAANCE - Dental Anesthesia Assistant National Certification Examination Practice Test

DAANCE Anesthetic Pharmacology 5