Pharmacology Flashcards
7 cards from real DAANCE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology flashcards as text
Which opioid analgesic is most commonly used as a component of balanced anesthesia in dental sedation due to its rapid onset and short duration?
Answer: Fentanyl
Fentanyl is preferred for dental sedation because of its rapid onset (1-2 minutes) and relatively short duration (30-60 minutes), making it ideal for titration.
A patient receiving nitrous oxide/oxygen sedation suddenly develops hypoxia. The MOST appropriate immediate action is to:
Answer: Administer 100% oxygen and discontinue nitrous oxide
When hypoxia occurs during N2O sedation, 100% oxygen must be administered immediately and nitrous oxide discontinued to prevent diffusion hypoxia and restore adequate oxygenation.
Midazolam produces anterograde amnesia primarily by acting on which receptor type?
Answer: GABA-A receptors
Midazolam enhances GABA-A receptor chloride ion conductance, producing CNS depression, anxiolysis, and anterograde amnesia.
Which drug is classified as an alpha-2 adrenergic agonist and is sometimes used as an adjunct in sedation for its anxiolytic and analgesic-sparing properties?
Answer: Dexmedetomidine
Dexmedetomidine is a highly selective alpha-2 adrenergic agonist that provides sedation, anxiolysis, and analgesia with minimal respiratory depression.
The maximum recommended dose of lidocaine WITH epinephrine for a healthy adult dental patient is:
Answer: 7 mg/kg up to 500 mg
Lidocaine with epinephrine has a maximum dose of 7 mg/kg, not to exceed 500 mg in a healthy adult, because epinephrine reduces systemic absorption.
Which benzodiazepine has the LONGEST elimination half-life and carries the greatest risk of cumulative sedation with repeated dosing?
Answer: Diazepam
Diazepam has an elimination half-life of 20-100 hours (plus active metabolites), making accumulation a significant concern with repeated doses.
Methemoglobinemia is a known toxic risk associated with excessive doses of which local anesthetic?
Answer: Prilocaine
Prilocaine is metabolized to o-toluidine, which oxidizes hemoglobin to methemoglobin, impairing oxygen-carrying capacity at higher doses.
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