CWCA Advanced Wound Therapies Flashcards

Ultrasonic debridement (low-frequency ultrasound) is beneficial in chronic wound care because it:

Answer: Disrupts biofilm and stimulates healing without damaging viable tissue

Low-frequency ultrasound uses cavitation and acoustic streaming to disrupt biofilm and enhance cellular activity while preserving viable granulation tissue.

Collagen-based wound dressings support healing by:

Answer: Providing a scaffold that attracts fibroblasts and supports tissue regeneration

Collagen dressings provide a biocompatible matrix that promotes fibroblast migration, collagen synthesis, and organized tissue regeneration.

Growth factor therapy in wound care, such as becaplermin (Regranex), is primarily indicated for:

Answer: Diabetic neuropathic foot ulcers not responding to standard care

Becaplermin (PDGF) is FDA-approved specifically for chronic diabetic neuropathic ulcers that have adequate blood supply but are not healing with standard therapy.

Maggot debridement therapy (MDT) is most effective for wounds with:

Answer: Slough and necrotic tissue in a chronic wound

Medicinal larvae selectively digest necrotic and sloughy tissue while secreting antimicrobial compounds, making MDT effective for chronic wounds with devitalized tissue.

Platelet-Rich Plasma (PRP) therapy promotes wound healing by:

Answer: Concentrating growth factors from the patient's own blood to stimulate tissue repair

PRP concentrates PDGF, TGF-β, VEGF, and other autologous growth factors that activate fibroblasts, endothelial cells, and keratinocytes to accelerate healing.

When applying NPWT to a wound near a blood vessel or organ, which foam interface material should be used?

Answer: White polyvinyl alcohol (PVA) foam

White PVA foam is denser and less aggressive than black polyurethane foam, making it safer near fragile structures such as blood vessels, tendons, and organs.