CTR Staging & Prognostic Factors 3

Question 1

In prostate cancer staging, what Gleason score range indicates Grade Group 5 (the highest grade)?

Accepted Answer

Gleason 9-10

Answer

Grade Group 5 encompasses Gleason scores 9 and 10, representing the most poorly differentiated prostate tumors.

Question 2

Which SEER summary stage category is used when cancer has spread only to regional lymph nodes with no distant spread?

Accepted Answer

Regional

Answer

SEER 'Regional' stage is assigned when cancer has spread to nearby lymph nodes or tissues but not to distant sites.

Question 3

A tumor registrar is abstracting a case where pathology shows extension of the tumor into but not through the serosa of the colon. Which T category applies in AJCC 8th edition?

Accepted Answer

T3

Answer

T3 colon tumors invade through the muscularis propria into pericolorectal tissues but do not penetrate the visceral peritoneum.

Question 4

Which receptor status combination confers the best prognosis in breast cancer?

Accepted Answer

ER+/PR+/HER2-

Answer

ER+/PR+/HER2- tumors are hormone receptor-positive and HER2-negative, associated with the best overall prognosis among the major subtypes.

Question 5

In the AJCC staging system, clinical staging (cTNM) is based on information available before which event?

Accepted Answer

First definitive treatment

Answer

Clinical staging uses all information obtained before the first definitive treatment, including physical exam, imaging, and biopsy results.

(CTR) Certified Tumor Registrar Practice Test

(CTR) Certified Tumor Registrar Practice Test

CTR Staging & Prognostic Factors 3