Practice Test Geeks(CTR) Certified Tumor Registrar Practice Test
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Staging & Prognostic Factors Flashcards

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  1. Which staging system is specifically designed for lymphomas and uses Roman numerals I through IV?

    Answer: Ann Arbor staging

    The Ann Arbor staging system (modified as Lugano classification) uses stages I–IV to describe lymphoma extent based on number and location of involved lymph node regions.

  2. In FIGO staging for gynecologic cancers, Stage IVB cervical cancer indicates:

    Answer: Distant metastasis beyond the pelvis

    FIGO Stage IVB cervical cancer denotes spread to distant organs beyond the true pelvis, including distant lymph nodes.

  3. A registrar notes 'angiolymphatic invasion present' on the pathology report. Which prognostic factor category does this represent?

    Answer: Lymphovascular invasion (LVI)

    Angiolymphatic invasion is synonymous with lymphovascular invasion (LVI) and is a recognized adverse prognostic factor recorded by tumor registrars.

  4. When a cancer presents with synchronous liver metastases at diagnosis, the AJCC M category is classified as:

    Answer: M1

    Liver metastases at diagnosis constitute distant spread, which is classified as M1 regardless of the number or size of metastatic lesions.

  5. The Oncotype DX Recurrence Score is a genomic prognostic tool used primarily for which cancer type?

    Answer: ER+/HER2- early-stage breast cancer

    Oncotype DX is validated for hormone receptor-positive, HER2-negative early-stage breast cancer to predict chemotherapy benefit and 10-year recurrence risk.

  6. In the AJCC 8th edition, which site introduced anatomically based prognostic stage groups that incorporate non-anatomic factors such as grade and biomarkers?

    Answer: Breast cancer

    The AJCC 8th edition breast cancer chapter introduced Prognostic Stage Groups that incorporate ER, PR, HER2, and grade alongside TNM anatomy.

  7. Which staging concept refers to cancer found incidentally in a specimen removed for another reason, with no preoperative suspicion?

    Answer: Incidental tumor (pT1a)

    Incidental tumors — such as prostate cancer found in a transurethral resection specimen — are often classified as pT1a or pT1b based on percentage of tissue involved.

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