CTP Donor & Recipient Evaluation 3

Question 1

A donor is found to have a hepatocellular carcinoma (HCC) incidentally discovered at procurement. Which organ may still be considered for transplantation in most protocols?

Accepted Answer

Kidneys

Answer

Kidneys are generally considered low risk for HCC transmission because primary liver malignancies rarely metastasize to the kidneys prior to procurement.

Question 2

Which hemodynamic parameter is used to guide fluid resuscitation during donor management to optimize organ perfusion?

Accepted Answer

Central venous pressure (CVP) of 4–10 mmHg

Answer

Maintaining CVP between 4–10 mmHg in brain-dead donors helps optimize cardiac preload without causing pulmonary edema.

Question 3

Donor-derived transmission of which organism is a well-documented risk requiring recipient prophylaxis in the early post-transplant period?

Accepted Answer

Toxoplasma gondii

Answer

Toxoplasma gondii can be transmitted from a seropositive donor heart to a seronegative recipient, necessitating post-transplant prophylaxis with TMP-SMX.

Question 4

In the context of expanded criteria donor (ECD) kidneys, which recipient group benefits most from use of these organs?

Accepted Answer

Older recipients with shorter expected remaining dialysis-free survival

Answer

Older recipients on dialysis gain survival benefit from ECD kidneys because even marginal kidney function often exceeds the mortality risk of remaining on dialysis.

Question 5

Which viral infection in a potential organ donor requires special disclosure to the transplant team and may restrict organ use to consenting recipients?

Accepted Answer

Active West Nile virus (WNV) infection

Answer

Active WNV infection in a donor can be transmitted through organs and carries significant neurological morbidity; use is restricted to life-threatening situations with recipient consent.

(CTP) Certified Transplant Preservationist Practice Test

(CTP) Certified Transplant Preservationist Practice Test

CTP Donor & Recipient Evaluation 3