Donor & Recipient Evaluation Flashcards
7 cards from real CTP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Donor & Recipient Evaluation flashcards as text
Which laboratory finding in a potential pancreas donor is considered the most concerning for pre-existing pancreatic dysfunction?
Answer: Hemoglobin A1c greater than 6.5%
An HbA1c greater than 6.5% indicates pre-existing diabetes in the donor, which is a contraindication to pancreas procurement for islet or whole-pancreas transplantation.
In evaluating a pediatric donor for organ donation, which anatomical consideration is most important when matching to a recipient?
Answer: Size and weight compatibility between donor and recipient
Size matching is critical for pediatric donors because organ-to-body size mismatch can lead to technical complications such as vascular thrombosis or poor engraftment.
A donor has nucleic acid testing (NAT) positive for HCV RNA. Which recipient population may still receive organs from this donor under current UNOS policy?
Answer: HCV-negative recipients who provide informed consent under specific protocols
With effective direct-acting antiviral therapy, NAT+ HCV donor organs may be transplanted into HCV-negative recipients who provide informed consent, per evolving UNOS/OPTN policy.
During neurological determination of death (NDD), which finding confirms the absence of brainstem reflexes as part of the clinical examination?
Answer: Absence of spontaneous respirations on apnea test with PCO2 >60 mmHg
A positive apnea test — no spontaneous respiratory effort with PaCO2 rising above 60 mmHg — confirms absence of medullary respiratory drive and supports brain death determination.
When evaluating a recipient candidate for simultaneous liver-kidney transplantation (SLK), which criterion is used to justify the kidney addition under current UNOS policy?
Answer: Sustained AKI or CKD with GFR ≤60 mL/min for ≥90 days, or ESRD on dialysis
UNOS SLK allocation policy requires sustained renal impairment (GFR ≤60 for ≥90 days, ESRD, or prolonged AKI) to justify using a kidney with the liver.
Which virological test result in a potential donor mandates automatic organ discard per most OPO protocols, regardless of organ type?
Answer: HIV RNA NAT positive (confirmed active HIV infection)
Confirmed active HIV infection (HIV RNA NAT positive) in a donor is an absolute contraindication to donation outside of the HIV Organ Policy Equity (HOPE) Act research protocols.
In the evaluation of a potential liver donor with a fatty liver (steatosis), which biopsy finding best predicts poor post-transplant graft function?
Answer: Macrovesicular steatosis >30% on biopsy
Macrovesicular steatosis exceeding 30% is associated with significantly increased risk of primary non-function and early allograft dysfunction after liver transplantation.