CT Non-Gynecologic Cytology

Question 1

Which type of lung carcinoma is most commonly identified in sputum cytology specimens due to its central airway location?

Accepted Answer

Squamous cell carcinoma

Answer

Adenocarcinoma

Answer

Small cell carcinoma

Answer

Large cell carcinoma

Question 2

Creola bodies found in respiratory cytology specimens are clusters of ciliated bronchial epithelial cells most associated with which condition?

Accepted Answer

Asthma

Answer

Pulmonary adenocarcinoma

Answer

Squamous cell carcinoma

Answer

Pulmonary infarction

Question 3

Which cytomorphologic feature is MOST characteristic of small cell carcinoma in bronchial brushing specimens?

Accepted Answer

Nuclear molding and salt-and-pepper chromatin

Answer

Abundant cytoplasm with prominent nucleoli

Answer

Intracytoplasmic mucin vacuoles

Answer

Keratin pearls and intercellular bridges

Question 4

Ferruginous bodies (asbestos bodies) identified in sputum cytology indicate prior exposure to which agent?

Accepted Answer

Asbestos fibers

Answer

Silica dust

Answer

Coal dust

Answer

Beryllium

Question 5

Which cytologic feature BEST distinguishes reactive type II pneumocytes from pulmonary adenocarcinoma cells in BAL specimens?

Accepted Answer

Cohesive flat sheets with uniform nuclei

Answer

Large nuclei with prominent nucleoli

Answer

Vacuolated cytoplasm

Answer

Single cells with nuclear membrane irregularity

Question 6

In bronchoalveolar lavage (BAL) specimens, what percentage of hemosiderin-laden macrophages (HLMs) is considered significant for pulmonary hemorrhage?

Accepted Answer

>20%

Answer

>5%

Answer

>40%

Answer

>60%

Question 7

A sputum specimen shows elongated, anucleate squamous cells with dense orange cytoplasm on Pap stain. What is the most likely interpretation?

Accepted Answer

Anucleate squames (oral contamination)

Answer

Squamous cell carcinoma

Answer

Reactive bronchial epithelium

Answer

Curschmann spirals