CSPT CSPT - Compounded Sterile Preparation Technician Parenteral Nutrition and IV Admixture Preparation Questions and Answers 2 — Questions and Answers
Question 1: Which complication is associated with too-rapid infusion of hypertonic dextrose in a TPN solution without adequate insulin?
- Hyperkalemia
- Hyperglycemia (Correct answer)
- Metabolic acidosis
- Hypocalcemia
Correct answer: Hyperglycemia
Rapid infusion of concentrated dextrose in TPN can cause hyperglycemia if insulin coverage is insufficient.
Question 2: What is the maximum recommended final concentration of dextrose in a peripherally administered IV admixture?
- 5%
- 10%
- 12.5% (Correct answer)
- 20%
Correct answer: 12.5%
Peripheral parenteral nutrition should not exceed 12.5% dextrose to avoid phlebitis and vein damage.
Question 3: Which amino acid solution component is responsible for providing nitrogen in TPN formulations?
- Dextrose
- Crystalline amino acids (Correct answer)
- Lipid emulsion
- Multivitamins
Correct answer: Crystalline amino acids
Crystalline amino acid solutions provide the nitrogen needed for protein synthesis and tissue maintenance in TPN.
Question 4: A compounding technician notices that a TPN admixture has a yellowish oily layer floating on top. This most likely indicates:
- Normal vitamin discoloration
- Lipid emulsion cracking or breaking (Correct answer)
- Acceptable dextrose oxidation
- Proper calcium phosphate precipitation
Correct answer: Lipid emulsion cracking or breaking
A floating oily layer in a 3-in-1 TPN indicates that the lipid emulsion has cracked (phase-separated), making it unsafe for use.
Question 5: Which vitamin is typically added to TPN separately and protected from light due to its photosensitivity?
- Vitamin C
- Vitamin B12
- Vitamin A (Correct answer)
- Thiamine
Correct answer: Vitamin A
Vitamin A is highly photosensitive and degrades rapidly when exposed to light, requiring light-protected IV tubing or bags.
Question 6: What USP chapter applies to endotoxin (pyrogen) testing of large-volume parenteral preparations like TPN?
- USP <71>
- <85> (Correct answer)
- <788>
- <1151>
Correct answer: <85>
USP <85> Bacterial Endotoxins Test is used to detect pyrogens in large-volume parenterals including TPN formulations.
CSPT CSPT - Compounded Sterile Preparation Technician Parenteral Nutrition and IV Admixture Preparation Questions and Answers 2
Which complication is associated with too-rapid infusion of hypertonic dextrose in a TPN solution without adequate insulin?