Hazardous Drug Compounding Flashcards

Which ventilation principle is required in a C-PEC used for hazardous drug compounding to protect personnel?

Answer: Inward airflow that captures contaminants before reaching the operator

Containment primary engineering controls (C-PECs) for hazardous drugs use inward (negative pressure) airflow to capture and contain contaminants, protecting the operator.

A pharmacy receives a new medication. Which resource is the FIRST to consult to determine if it requires hazardous drug handling precautions?

Answer: NIOSH List of Antineoplastic and Other Hazardous Drugs

The NIOSH List of Hazardous Drugs is the primary reference used to classify whether a drug requires special handling precautions in healthcare settings.

When compounding a hazardous drug, a technician accidentally spills a small amount on the C-PEC work surface. What is the correct immediate action?

Answer: Remove all items, don a second pair of gloves, and use the HD spill kit

A spill inside the C-PEC requires stopping work, donning additional PPE, and using the designated hazardous drug spill kit per USP protocols.

Under USP , what is the minimum required air pressure relationship between the hazardous drug buffer room and the ante-room?

Answer: Buffer room must be negative relative to ante-room

USP requires the hazardous drug buffer room to maintain negative pressure relative to the ante-room to prevent contamination from escaping into adjoining areas.

Which of the following is classified as a Group 2 hazardous drug under NIOSH criteria?

Answer: Warfarin (reproductive risk only, non-antineoplastic)

NIOSH Group 2 includes non-antineoplastic drugs that meet one or more hazard criteria; warfarin poses a reproductive risk, placing it in Group 2.

A technician must transport a completed hazardous IV preparation from the cleanroom to the patient care unit. How should it be packaged?

Answer: In a sealed, clearly labeled, leak-proof container or bag

Hazardous drug preparations must be transported in sealed, leak-proof, clearly labeled containers to prevent accidental exposure during transit.

What is the purpose of performing a surface sampling (wipe test) in areas where hazardous drugs are handled?

Answer: To detect and quantify surface contamination with hazardous drug residue

Wipe testing detects residual hazardous drug surface contamination, helping verify that cleaning and decontamination procedures are effective.