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COCN Hematologic Malignancies Flashcards

6 cards from real COCN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Which type of leukemia is most commonly diagnosed in adults over 65 years old in the United States?

    Answer: Chronic lymphocytic leukemia (CLL)

    CLL is the most common adult leukemia in the US, predominantly affecting older adults.

  2. A patient with multiple myeloma is at highest risk for which skeletal complication?

    Answer: Pathologic fractures

    Myeloma cells stimulate osteoclasts and inhibit osteoblasts, leading to lytic lesions and pathologic fractures.

  3. The Philadelphia chromosome, resulting from a translocation between chromosomes 9 and 22, is the hallmark of which leukemia?

    Answer: Chronic myeloid leukemia (CML)

    The t(9;22) translocation creates the BCR-ABL fusion gene, which drives CML and is targeted by imatinib.

  4. Which staging system is used specifically for non-Hodgkin lymphoma and Hodgkin lymphoma?

    Answer: Ann Arbor staging

    The Ann Arbor staging system (Stages I–IV) classifies lymphoma based on the number and location of involved lymph node regions.

  5. A nurse is caring for a patient with multiple myeloma. Which lab finding is most indicative of disease activity?

    Answer: Elevated serum protein electrophoresis (M-protein spike)

    The M-protein spike on SPEP reflects the monoclonal immunoglobulin produced by malignant plasma cells.

  6. Tumor lysis syndrome is most likely to occur in patients receiving treatment for which hematologic malignancy?

    Answer: Bulky or rapidly proliferating lymphomas and acute leukemias

    TLS occurs when rapid cell destruction releases intracellular contents, most common in high-burden, rapidly proliferating cancers.

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