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COCN Hematologic Malignancies Flashcards

6 cards from real COCN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 COCN Hematologic Malignancies flashcards as text

  1. A patient with CLL develops hemolytic anemia and thrombocytopenia caused by autoimmune destruction. This is known as:

    Answer: Evans syndrome

    Evans syndrome is the combination of autoimmune hemolytic anemia and immune thrombocytopenia, seen in some CLL patients.

  2. Which nursing assessment finding in a patient with acute leukemia would prompt the nurse to immediately notify the physician?

    Answer: Sudden onset of severe headache and visual changes

    Sudden headache and visual changes in a leukemia patient suggest CNS leukemia or intracranial bleeding, requiring urgent evaluation.

  3. Rituximab is a monoclonal antibody used in B-cell lymphomas that targets which surface antigen?

    Answer: CD20

    Rituximab targets CD20, a surface antigen expressed on most B-cell lymphomas, leading to cell lysis and apoptosis.

  4. A myeloma patient receiving bortezomib is at risk for which notable peripheral neuropathy-related side effect?

    Answer: Chemotherapy-induced peripheral neuropathy (CIPN)

    Bortezomib commonly causes CIPN, manifesting as tingling, pain, and numbness in hands and feet.

  5. Which finding would the nurse expect in a patient with symptomatic chronic lymphocytic leukemia (CLL) on physical examination?

    Answer: Splenomegaly and lymphadenopathy

    CLL characteristically causes progressive lymphadenopathy and splenomegaly as malignant B-lymphocytes accumulate in lymphoid tissue.

  6. Allopurinol is administered prophylactically before chemotherapy in high-risk hematologic malignancy patients primarily to prevent:

    Answer: Uric acid nephropathy from tumor lysis syndrome

    Allopurinol blocks xanthine oxidase, reducing uric acid production and preventing urate crystal deposition in renal tubules during TLS.

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