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COCN Hematologic Malignancies Flashcards

6 cards from real COCN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Which finding on a peripheral blood smear is characteristic of chronic myeloid leukemia (CML)?

    Answer: Left shift with cells at all stages of myeloid maturation

    CML shows a left shift with myeloid cells at all maturation stages, reflecting uncontrolled granulocyte production.

  2. A patient with Hodgkin lymphoma reports drenching night sweats, unexplained fever, and 12% weight loss. These are classified as:

    Answer: B symptoms

    B symptoms (fever >38°C, drenching night sweats, >10% weight loss) indicate systemic disease and affect staging in lymphoma.

  3. Which medication class is the standard first-line treatment for CML targeting the BCR-ABL oncoprotein?

    Answer: Tyrosine kinase inhibitors (TKIs)

    TKIs such as imatinib, dasatinib, and nilotinib directly inhibit BCR-ABL kinase activity in CML.

  4. Reed-Sternberg cells are pathognomonic for which lymphoma type?

    Answer: Hodgkin lymphoma

    Large binucleated Reed-Sternberg cells with prominent owl-eye nucleoli are the defining histologic feature of Hodgkin lymphoma.

  5. Which electrolyte imbalance is NOT a feature of tumor lysis syndrome (TLS)?

    Answer: Hypercalcemia

    TLS causes hypocalcemia (not hypercalcemia) due to phosphate binding calcium as phosphate is released from lysed cells.

  6. A patient with multiple myeloma has a serum calcium of 12.8 mg/dL. Which nursing intervention is the priority?

    Answer: Administer IV normal saline hydration

    Aggressive IV hydration with normal saline is the first-line treatment for hypercalcemia to promote renal calcium excretion.

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