COCN COCN Hematologic Malignancies 3

Question 1

A patient with CLL develops hemolytic anemia and thrombocytopenia caused by autoimmune destruction. This is known as:

Accepted Answer

Evans syndrome

Answer

Evans syndrome is the combination of autoimmune hemolytic anemia and immune thrombocytopenia, seen in some CLL patients.

Question 2

Which nursing assessment finding in a patient with acute leukemia would prompt the nurse to immediately notify the physician?

Accepted Answer

Sudden onset of severe headache and visual changes

Answer

Sudden headache and visual changes in a leukemia patient suggest CNS leukemia or intracranial bleeding, requiring urgent evaluation.

Question 3

Rituximab is a monoclonal antibody used in B-cell lymphomas that targets which surface antigen?

Accepted Answer

CD20

Answer

Rituximab targets CD20, a surface antigen expressed on most B-cell lymphomas, leading to cell lysis and apoptosis.

Question 4

A myeloma patient receiving bortezomib is at risk for which notable peripheral neuropathy-related side effect?

Accepted Answer

Chemotherapy-induced peripheral neuropathy (CIPN)

Answer

Bortezomib commonly causes CIPN, manifesting as tingling, pain, and numbness in hands and feet.

Question 5

Which finding would the nurse expect in a patient with symptomatic chronic lymphocytic leukemia (CLL) on physical examination?

Accepted Answer

Splenomegaly and lymphadenopathy

Answer

CLL characteristically causes progressive lymphadenopathy and splenomegaly as malignant B-lymphocytes accumulate in lymphoid tissue.

COCN Test Practice Test