COCN COCN Hematologic Malignancies 3

Question 1

A patient with CLL develops hemolytic anemia and thrombocytopenia caused by autoimmune destruction. This is known as:

Accepted Answer

Evans syndrome

Answer

Richter transformation

Answer

Tumor lysis syndrome

Answer

Graft-versus-host disease

Question 2

Which nursing assessment finding in a patient with acute leukemia would prompt the nurse to immediately notify the physician?

Accepted Answer

Sudden onset of severe headache and visual changes

Answer

ANC of 1800/mm³

Answer

Platelet count of 90,000/mm³

Answer

Mild fatigue after ambulation

Question 3

Rituximab is a monoclonal antibody used in B-cell lymphomas that targets which surface antigen?

Accepted Answer

CD20

Answer

CD3

Answer

CD52

Answer

HER2

Question 4

A myeloma patient receiving bortezomib is at risk for which notable peripheral neuropathy-related side effect?

Accepted Answer

Chemotherapy-induced peripheral neuropathy (CIPN)

Answer

Autonomic neuropathy only

Answer

Optic neuritis

Answer

Ototoxicity

Question 5

Which finding would the nurse expect in a patient with symptomatic chronic lymphocytic leukemia (CLL) on physical examination?

Accepted Answer

Splenomegaly and lymphadenopathy

Answer

Absent lymph nodes

Answer

Hepatic atrophy

Answer

Peripheral edema without lymph node involvement

Question 6

Allopurinol is administered prophylactically before chemotherapy in high-risk hematologic malignancy patients primarily to prevent:

Accepted Answer

Uric acid nephropathy from tumor lysis syndrome

Answer

Neutropenic fever

Answer

Cardiotoxicity

Answer

Mucositis