COCN COCN Hematologic Malignancies 2

Question 1

Which finding on a peripheral blood smear is characteristic of chronic myeloid leukemia (CML)?

Accepted Answer

Left shift with cells at all stages of myeloid maturation

Answer

Blast crisis only

Answer

Auer rods

Answer

Smudge cells

Question 2

A patient with Hodgkin lymphoma reports drenching night sweats, unexplained fever, and 12% weight loss. These are classified as:

Accepted Answer

B symptoms

Answer

A symptoms

Answer

C symptoms

Answer

Constitutional grade I

Question 3

Which medication class is the standard first-line treatment for CML targeting the BCR-ABL oncoprotein?

Accepted Answer

Tyrosine kinase inhibitors (TKIs)

Answer

Alkylating agents

Answer

Anthracyclines

Answer

Anti-CD20 monoclonal antibodies

Question 4

Reed-Sternberg cells are pathognomonic for which lymphoma type?

Accepted Answer

Hodgkin lymphoma

Answer

Diffuse large B-cell lymphoma

Answer

Follicular lymphoma

Answer

Mantle cell lymphoma

Question 5

Which electrolyte imbalance is NOT a feature of tumor lysis syndrome (TLS)?

Accepted Answer

Hypercalcemia

Answer

Hyperkalemia

Answer

Hyperphosphatemia

Answer

Hyperuricemia

Question 6

A patient with multiple myeloma has a serum calcium of 12.8 mg/dL. Which nursing intervention is the priority?

Accepted Answer

Administer IV normal saline hydration

Answer

Restrict oral fluids to 1L/day

Answer

Encourage a high-calcium diet

Answer

Apply warm compresses to the extremities