Treatment Planning Flashcards

Before transfusing a patient with known anti-K, which blood product selection is appropriate?

Answer: K-antigen-negative, crossmatch-compatible red cells

Patients with clinically significant alloantibodies must receive antigen-negative, compatible units.

Which product is the best choice to correct bleeding due to hypofibrinogenemia?

Answer: Cryoprecipitate

Cryoprecipitate is rich in fibrinogen, factor VIII, vWF, and factor XIII.

Irradiated blood products are indicated in treatment plans to prevent:

Answer: Transfusion-associated graft-versus-host disease

Irradiation inactivates donor T lymphocytes that could cause TA-GVHD in susceptible recipients.

A neonate requires red cells and the mother has anti-D. Which unit is most appropriate?

Answer: D-negative red cells compatible with maternal serum

Maternal anti-D may be present in the infant, so D-negative units compatible with maternal plasma are chosen.

Leukoreduced cellular blood products are used primarily to reduce which complication?

Answer: Febrile nonhemolytic transfusion reactions and HLA alloimmunization

Removing leukocytes lowers cytokine-mediated febrile reactions, HLA alloimmunization, and CMV transmission.

A patient has repeated anaphylactic reactions to plasma-containing products and is IgA deficient with anti-IgA. Which product modification is preferred?

Answer: Washed red cells or IgA-deficient donor products

Washing removes plasma IgA, or IgA-deficient donor products can be used to prevent anaphylaxis.

Expected increment from one unit of packed red cells in an average adult is approximately:

Answer: Hemoglobin 1 g/dL or hematocrit 3%

One unit of RBCs raises hemoglobin by about 1 g/dL and hematocrit by about 3% in an average adult.