CMSRN Study Guide 2026

Everything you need to pass the CMSRN exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 CMSRN Exam Format at a Glance

150
Questions
180 min
Time Limit
70%
Passing Score

📚 CMSRN Topics to Study (45)

Anesthetist · 11 cardsCardiac Vascular · 11 cardsGeneral · 11 cardsGuide · 11 cardsMedical-Surgical Nursing MCQ · 11 cardsGeneral · 11 cardsTrivia · 11 cardsPerioperative · 11 cardsTransplant · 11 cardsGastrointestinal and Hepatic Care · 7 cardsGastrointestinal and Hepatic Care · 7 cardsGastrointestinal and Hepatic Care · 7 cardsGeneral · 7 cardsGeneral · 7 cardsCMSRN - Medical-Surgical Nursing Cardiovascular and Hematological Care Questions and Answers · 6 cardsCMSRN - Medical-Surgical Nursing Cardiovascular and Hematological Care Questions and Answers · 6 cardsFREE CMSRN Anesthetist Questions and Answers · 6 cardsFREE CMSRN Anesthetist Questions and Answers · 6 cardsFREE CMSRN Cardiac Vascular Questions and Answers · 6 cardsFREE CMSRN Cardiac Vascular Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing General Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing General Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Guide Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Guide Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing MCQ Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing MCQ Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Trivia Questions and Answers · 6 cardsFREE CMSRN Medical-Surgical Nursing Trivia Questions and Answers · 6 cards

✍️ Sample CMSRN Questions & Answers

1. A nurse is caring for a patient with heart failure who develops frothy, pink-tinged sputum and severe dyspnea. What is the priority nursing intervention?
Position the patient upright and administer oxygen

Frothy pink-tinged sputum indicates pulmonary edema, and the priority is to position upright to reduce preload and administer supplemental oxygen.

2. A patient with hepatic encephalopathy is prescribed lactulose. What is the primary therapeutic goal of this medication?
Decrease serum ammonia levels

Lactulose acidifies the colon, trapping ammonia as ammonium ion and promoting its fecal excretion, thereby reducing the serum ammonia causing encephalopathy.

3. A nurse is caring for a patient receiving a blood transfusion who develops fever, flank pain, and dark urine. What is the priority nursing action?
Stop the transfusion immediately

These symptoms indicate an acute hemolytic transfusion reaction, requiring immediate cessation of the transfusion to prevent further harm.

4. A patient who just had a colostomy surgery expresses distress about body image changes. Which nursing intervention is the priority?
Allow the patient to verbalize feelings and validate their concerns

Establishing therapeutic communication by allowing the patient to express feelings and validating concerns is the priority before education or referrals when addressing psychosocial distress.

5. Except for the following, all of the following list phosphodiasterase inhibitors:
Vasoconstrictor

Phosphodiesterase inhibitors (PDEIs) like milrinone are known for their positive inotropic effects (increasing cardiac contractility) and their ability to cause vasodilation, which decreases systemic vascular resistance (SVR). They achieve this by preventing the breakdown of cyclic AMP (cAMP), leading to increased intracellular calcium in cardiac cells and smooth muscle relaxation in blood vessels. Therefore, 'Vasoconstrictor' is the characteristic that does NOT describe the action of phosphodiesterase inhibitors.

6. A patient with a new diagnosis of atrial fibrillation asks why anticoagulation therapy is necessary. What is the nurse's best response?
Atrial fibrillation causes blood to pool in the atria, increasing the risk of clot formation and stroke

In atrial fibrillation, ineffective atrial contraction causes blood stasis, increasing thrombus formation risk and subsequent stroke.

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Your CMSRN Study Path
1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation