CLS Pediatric Lipid Disorders 2

Question 1

At what age does the American Academy of Pediatrics recommend universal lipid screening for children?

Accepted Answer

Age 9-11 years

Answer

Universal lipid screening is recommended for all children at ages 9-11 years and again at ages 17-21 years.

Question 2

Which lipoprotein particle is most atherogenic in children with familial hypercholesterolemia?

Accepted Answer

LDL-C

Answer

LDL-C is the primary atherogenic particle in heterozygous and homozygous familial hypercholesterolemia in children.

Question 3

A 10-year-old presents with tendon xanthomas and an LDL-C of 520 mg/dL. Which diagnosis is most consistent?

Accepted Answer

Homozygous familial hypercholesterolemia

Answer

Tendon xanthomas with LDL-C >400 mg/dL in a child strongly suggests homozygous familial hypercholesterolemia.

Question 4

Which statin is FDA-approved for use in children as young as 8 years of age with heterozygous FH?

Accepted Answer

Pravastatin

Answer

Pravastatin is approved for children aged 8 and older with heterozygous familial hypercholesterolemia.

Question 5

In pediatric hypertriglyceridemia, which triglyceride level threshold raises concern for pancreatitis risk?

Accepted Answer

>500 mg/dL

Answer

Triglyceride levels exceeding 500 mg/dL significantly increase pancreatitis risk and require prompt intervention.

(CLS) Clinical Lipid Specialist Certification Practice Test