CLS Hematology and Coagulation Flashcards
6 cards from real CLS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 CLS Hematology and Coagulation flashcards as text
Which stain is routinely used to identify malaria parasites on a peripheral blood smear?
Answer: Wright-Giemsa stain
Wright-Giemsa stain is the standard stain for peripheral blood smear examination, including identification of intraerythrocytic malaria parasites.
Sickle cell disease results from a mutation in which protein?
Answer: Hemoglobin
Sickle cell disease is caused by a point mutation (Glu→Val) in the beta-globin gene, producing abnormal hemoglobin S.
The aPTT (activated Partial Thromboplastin Time) is primarily used to assess which pathway and monitor which therapy?
Answer: Intrinsic and common pathways; heparin monitoring
aPTT evaluates the intrinsic and common coagulation pathways and is the primary test used to monitor unfractionated heparin therapy.
Hemolytic Uremic Syndrome (HUS) is classically characterized by which triad?
Answer: Microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure
HUS presents with the classic triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure, often following E. coli O157:H7 infection.
In a complete blood count, what does a high RDW (Red Cell Distribution Width) indicate?
Answer: Greater variation in red cell size (anisocytosis)
RDW quantifies variation in red blood cell size (anisocytosis); an elevated RDW indicates a heterogeneous population of red cells.
Which vitamin is essential for the gamma-carboxylation and activation of clotting Factors II, VII, IX, and X?
Answer: Vitamin K
Vitamin K is required for gamma-carboxylation of Factors II, VII, IX, and X, enabling them to bind calcium and become functional.