CLE Anatomy & Physiology of Lactation 3

Question 1

Lactogenesis II is defined as the onset of copious milk secretion. When does it typically occur?

Accepted Answer

Between 30 and 72 hours postpartum

Answer

Lactogenesis II, triggered by the drop in progesterone after placental delivery and sustained prolactin, typically results in milk 'coming in' between 30–72 hours postpartum.

Question 2

Which stage of lactation describes the secretory differentiation of mammary epithelial cells that begins mid-pregnancy?

Accepted Answer

Lactogenesis I

Answer

Lactogenesis I (secretory differentiation) occurs around mid-pregnancy when alveolar cells differentiate into secretory lactocytes capable of producing small amounts of colostrum.

Question 3

What distinguishes colostrum from mature breast milk in terms of protein content?

Accepted Answer

Colostrum has higher protein concentration than mature milk

Answer

Colostrum is concentrated with protein (especially secretory IgA, lactoferrin, and growth factors) at roughly 2–3 times the protein concentration of mature milk.

Question 4

Galactopoiesis refers to which phase of lactation?

Accepted Answer

Ongoing maintenance of established milk supply

Answer

Galactopoiesis (also called Lactogenesis III) describes the autocrine-driven maintenance of milk supply that depends on frequent and effective milk removal.

Question 5

The Feedback Inhibitor of Lactation (FIL) regulates milk supply through which mechanism?

Accepted Answer

It is a whey protein in accumulated milk that suppresses further secretion locally

Answer

FIL is a whey protein produced in the alveoli that accumulates when milk is not removed, signaling lactocytes to slow production via autocrine control.

(CLE) Certified Lactation Educator Practice Test

(CLE) Certified Lactation Educator Practice Test

CLE Anatomy & Physiology of Lactation 3