CHT Laboratory Management & Safety 3

Question 1

What is the purpose of an Internal Proficiency Testing (IPT) program when no approved external PT program is available for a test?

Accepted Answer

The lab uses split samples, previously tested specimens, or reference materials to verify ongoing accuracy

Answer

When external PT is unavailable, CLIA requires labs to use an equivalent process such as split-sample testing or reference material analysis twice per year.

Question 2

Which OSHA standard is most directly relevant to worker safety in the histocompatibility laboratory when handling patient specimens?

Accepted Answer

Bloodborne Pathogens Standard (29 CFR 1910.1030)

Answer

The OSHA Bloodborne Pathogens Standard requires engineering controls, PPE, training, hepatitis B vaccination, and exposure control plans for workers handling blood and tissues.

Question 3

What is a 'laboratory information system' (LIS) and why is it critical in the histocompatibility laboratory?

Accepted Answer

A software system that manages patient data, test orders, results, and reports to ensure accurate specimen tracking and result reporting

Answer

The LIS manages the full workflow from specimen receipt to result release, maintains the patient HLA type history, tracks crossmatch results, and interfaces with transplant center systems.

Question 4

What does the ASHI accreditation standard require regarding competency assessment of laboratory personnel?

Accepted Answer

Annual documented competency assessment for all personnel performing patient testing

Answer

ASHI and CLIA require annual documented competency evaluations for all testing personnel covering all procedures they perform, including direct observation and result review.

Question 5

What is the primary risk of improper specimen labeling in a histocompatibility laboratory?

Accepted Answer

Patient misidentification leading to an incompatible crossmatch result being applied to the wrong patient and fatal transplant error

Answer

In transplantation, a mislabeled specimen can result in an incorrect crossmatch or HLA type being matched to the wrong patient, potentially causing a fatal incompatible transplant.

CHT - Certified Histocompatibility Technologist Practice Test

CHT - Certified Histocompatibility Technologist Practice Test

CHT Laboratory Management & Safety 3