CHS Pharmacology & Medication Management 4

Question 1

Vitamin E supplementation prior to HBO therapy has been studied for its role in:

Accepted Answer

Reducing pulmonary oxygen toxicity through antioxidant mechanisms

Answer

Vitamin E is a fat-soluble antioxidant studied for its potential to attenuate pulmonary oxygen toxicity by scavenging reactive oxygen species during HBO courses.

Question 2

A patient taking tramadol is referred for HBO therapy. The specific concern regarding this opioid analgesic is:

Accepted Answer

Tramadol lowers seizure threshold, compounding CNS oxygen toxicity risk

Answer

Tramadol is known to lower the seizure threshold, which is additive to the CNS oxygen toxicity risk already present during HBO treatments at depth.

Question 3

Sulfamylon (mafenide acetate) is commonly used in wound care for burn patients in HBO. The primary pharmacological concern is:

Accepted Answer

It is a carbonic anhydrase inhibitor that can cause metabolic acidosis

Answer

Mafenide acetate inhibits carbonic anhydrase, potentially causing metabolic acidosis, which must be monitored during intensive burn wound care combined with HBO.

Question 4

Which sedation agent is most appropriate for use in a monoplace hyperbaric chamber when a patient cannot tolerate the treatment without pharmacological assistance?

Accepted Answer

Oral benzodiazepine (e.g., lorazepam) administered 30 minutes before treatment

Answer

Oral benzodiazepines given before chamber entry are the safest anxiolytic approach for monoplace HBO because they avoid the need for electronic infusion devices inside the chamber.

Question 5

The pharmacokinetics of inhaled anesthetic agents (e.g., isoflurane) are altered in hyperbaric environments primarily because:

Accepted Answer

Increased partial pressures reduce the MAC required for anesthesia

Answer

The minimum alveolar concentration (MAC) of inhaled anesthetics decreases predictably as ambient pressure increases, following Henry's Law principles regarding partial pressures.

(CHS) Certified Hypertension Specialist Practice Test

(CHS) Certified Hypertension Specialist Practice Test

CHS Pharmacology & Medication Management 4