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Pharmacology and Sedation Flashcards

6 cards from real CGRN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 Pharmacology and Sedation flashcards as text

  1. A patient on chronic methadone therapy needs endoscopy with moderate sedation. How does this affect opioid dosing?

    Answer: Higher opioid doses may be needed due to tolerance

    Chronic opioid users develop tolerance requiring higher doses of procedural opioids.

  2. Which topical pharyngeal anesthetic for EGD carries a risk of methemoglobinemia?

    Answer: Benzocaine spray

    Benzocaine carries significant risk of methemoglobinemia and impairs the gag reflex.

  3. What is the mechanism by which sucralfate promotes gastric ulcer healing?

    Answer: Forms a protective barrier over the ulcer crater

    Sucralfate polymerizes in acidic pH and binds to proteins at the ulcer base, forming a physical barrier.

  4. A patient on phenytoin is given IV diazepam for endoscopy. What interaction should the nurse anticipate?

    Answer: Phenytoin levels may increase, leading to toxicity

    Diazepam and phenytoin compete for protein binding and metabolic pathways, potentially increasing free phenytoin.

  5. Which diabetes medications should be held on the morning of endoscopy?

    Answer: Sulfonylureas and prandial insulin doses

    Sulfonylureas and prandial insulin stimulate insulin release or cover meals, risking hypoglycemia during fasting.

  6. What is the role of simethicone when administered before upper endoscopy?

    Answer: To reduce surface tension of gas bubbles, improving mucosal visualization

    Simethicone is an anti-foaming agent that disperses gas bubbles to improve mucosal visualization.

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