CET CET Medication Safety & Pharmacology 2 — Questions and Answers
Question 1: Glucagon is sometimes administered during endoscopy procedures primarily to:
- Increase peristalsis
- Reduce GI motility temporarily (Correct answer)
- Control active bleeding
- Treat post-procedure infection
Correct answer: Reduce GI motility temporarily
Glucagon relaxes smooth muscle in the GI tract, temporarily reducing motility to improve visualization and ease instrumentation during some endoscopy procedures.
Question 2: Simethicone added to irrigation water during endoscopy serves what purpose?
- Prevents infection
- Reduces foam and bubbles in the GI lumen (Correct answer)
- Induces light sedation
- Controls mucosal bleeding
Correct answer: Reduces foam and bubbles in the GI lumen
Simethicone is an anti-foaming agent that breaks up intraluminal bubbles and foam, significantly improving mucosal visualization during endoscopy.
Question 3: What is the first-line medication for treating anaphylaxis that occurs during an endoscopy procedure?
- Atropine
- Epinephrine (Correct answer)
- Midazolam
- Glucagon
Correct answer: Epinephrine
Epinephrine (adrenaline) is the first-line treatment for anaphylaxis because it reverses bronchospasm, vasodilation, and urticaria through alpha and beta adrenergic stimulation.
Question 4: Erythromycin administered before emergent upper endoscopy in an upper GI bleed patient is intended to:
- Treat Helicobacter pylori infection
- Clear the stomach of blood to improve visualization (Correct answer)
- Reduce patient anxiety
- Decrease gastric acid secretion
Correct answer: Clear the stomach of blood to improve visualization
Erythromycin acts as a motilin receptor agonist to accelerate gastric emptying, clearing blood and clots to improve visualization at emergent upper endoscopy.
Question 5: Which medication class may be contraindicated in patients with a known sulfite allergy requiring endoscopy sedation?
- Benzodiazepines
- Opioids
- Propofol (Correct answer)
- Anticholinergics
Correct answer: Propofol
Some propofol formulations contain sodium metabisulfite as a preservative, which can trigger reactions in sulfite-sensitive patients.
Question 6: Atropine is most likely to be used during endoscopy to treat which complication?
- Bronchospasm
- Symptomatic bradycardia (Correct answer)
- Hypertensive urgency
- Nausea and vomiting
Correct answer: Symptomatic bradycardia
Atropine is the first-line medication for symptomatic bradycardia that may result from a vasovagal response during endoscopy.
CET CET Medication Safety & Pharmacology 2
Glucagon is sometimes administered during endoscopy procedures primarily to: